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Thank you for visiting our website, we hope you find what you're looking for. We've done our research and back our products on the leading science and peer reviewed studies. Please continue reading for a deep dive into colloidal silver.
FDA Disclaimer:
Our website offers colloidal silver products for purchase which are
believed to have various health benefits. While colloidal silver is widely used and well-regarded in alternative health circles, it is important to note that individual results may vary.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Use at your own risk. Noble Alternative assumes no liability for product misuse.
Silver nanoparticles as a new generation of antimicrobials -
PubMed (nih.gov)
Silver nanoparticles have emerged as a promising antimicrobial agent in the field of medicine. Traditionally, silver compounds were used for supporting rapid skin barrier recovery, tissue comfort, and deep surface cleaning. but their use shifted as synthetic pharmaceutical options emerged. However, the utilization of metallic silver in the form of nanoparticles has regained significance due to nanotechnology advancements. Silver nanoparticles exhibit enhanced antimicrobial properties, especially against antibiotic-resistance bacteria. They are being incorporated into various medical applications such as silver-based dressings and nanogels. In contrast, the safety of colloidal silver, a suspension of tiny silver particles in liquid, for ingestion remains a subject of debate. Differentiating between 20 parts per million (PPM)and 500 PPM colloidal silver, the lower concentration is generally considered safer, while the higher concentration may pose health risks such as argyria – a condition resulting in a permanent silver-blue discoloration of the skin or eyes.
Source: https://pubmed.ncbi.nlm.nih.gov/18854209/
Rai M, Yadav A, Gade A. Silver nanoparticles as a new generation of
antimicrobials. Biotechnol Adv. 2009 Jan-Feb;27(1):76-83. doi:
10.1016/j.biotechadv.2008.09.002. Epub 2008 Sep 30. PMID: 18854209.
Impact of silver nanoparticles on human cells: effect of particle size
- PubMed (nih.gov)
This study examined the impact of silver nanoparticles of varying sizes
on human cells. Researchers found that smaller particles had observable
deleterious effects on cell morphology and membrane integrity, leading
to increased levels of reactive oxygen species (ROS) within the cells and
cell cycle arrest. Additionally, apoptosis was observed in a small
percentage of exposed cells. The toxicity and cellular responses were
found to be size-dependent, with smaller nanoparticles entering cells
more easily and causing higher toxic effects. This highlights the
importance of focusing on low parts per million (ppm) levels of silver
nanoparticles, which are considered safer for ingestion, although long-
term ingestion is not recommended.
Source: https://pubmed.ncbi.nlm.nih.gov/20795913/
Liu W, Wu Y, Wang C, Li HC, Wang T, Liao CY, Cui L, Zhou QF, Yan B, Jiang
GB. Impact of silver nanoparticles on human cells: effect of particle size.
Nanotoxicology. 2010 Sep;4(3):319-30. doi: 10.3109/17435390.2010.483745. PMID: 20795913.
** This is why NOBLE ALTERNATIVE focuses on lower ppm levels such as 10ppm through 60 ppm. Lower ppm levels are safer for ingestion although not recommended for long-term ingestion.
In vivo efficacy of silver nanoparticles against Syphacia muris
infected laboratory Wistar rats - PubMed (nih.gov)
This study investigated the in vivo efficacy of silver nanoparticles in
treating Syphacia muris infections in laboratory Wistar rats. The
researchers found that the administration of silver nanoparticles
resulted in substantial alterations in the worms collected from the
treated rats, leading to damage to their body structures and
physiological functions. The treated rats displayed improved health
without significant toxicity to their liver, kidney, and spleen. Overall, the
study suggests that silver nanoparticles have the potential to be a safe
and effective treatment for pinworm infections in laboratory settings,
offering a promising solution without significant side effects.
Research published on PubMed explores the microscopic and broad-spectrum physical properties of silver nanoparticles in laboratory settings
Source: https://pubmed.ncbi.nlm.nih.gov/38009151/
Fol MF, Hamdi SA, Abdel-Rahman HA, Mostafa NA. In vivo efficacy of
silver nanoparticles against Syphacia muris infected laboratory Wistar rats. J Parasit Dis. 2023 Dec;47(4):744-756. doi: 10.1007/s12639-023-01607-5. Epub 2023 Aug 5. PMID: 38009151; PMCID: PMC10667209.
Prescription, over-the-counter (OTC), herbal, and other treatments
and preventive uses for COVID-19 - PMC (nih.gov)
Colloidal silver, containing silver nanoparticles, has been found to exhibit
antifungal, antibacterial, and antiviral properties. Studies have shown
that negatively charged silver nanoparticles have higher antibacterial
activity compared to traditional colloidal silver.
Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237643/
Yáñez JA, Chung SA, Román BR, Hernández-Yépez PJ, Garcia-Solorzano FO, Del-Aguila-Arcentales S, Inga-Berrospi F, Mejia CR, Alvarez-Risco A. Prescription, over-the-counter (OTC), herbal, and other treatments and preventive uses for COVID-19. Environmental and Health Management of Novel Coronavirus Disease (COVID-19 ). 2021:379–416. doi:
10.1016/B978-0-323-85780-2.00001-9. Epub 2021 Jun 28. PMCID: PMC8237643.